Alzheimer’s Disease

Topic

Discussion: Alzheimer’s Disease

Instructions

Elaborate on the Topic for Your Critical Review

This assignment will be a continuation of the written assignment from Week One. Research a minimum of three peer-reviewed articles in addition to information from your text on the disorder you chose in Week One. Consider the key classes of drugs used to treat the disorder you chose in Week One and explain their action at the neurotransmitter system involved in the disease process. Analyze and describe the agonist-antagonist activity of the drugs and the receptor types and subtypes involved in the disorder. Elaborate on the receptor agonist-antagonist actions of the drugs and describe the most common side effects seen with these drugs. Evaluate the risk-benefits of drug use for this disorder.
The paper:
  • Must be four double-spaced pages in length, excluding title page and references page, and it must be formatted according to APA style as outlined in the Ashford Writing Center.
  • Must include a title page with the following:
    • Title of paper
    • Your name
    • Course name and number
    • Your instructor’s name
    • Date submitted
  • Must address the topic of the paper with critical thought.
  • Must use at least three peer-reviewed sources in addition to the text.
  • Must document all sources in APA style as outlined in the Ashford Writing Center.
  • Must include a separate references page that is formatted according to APA style as outlined in the Ashford Writing Center.

Articles

Macluluch, A. M. J., Anand, A., Davis, D. H. J., Jackson, T., Barugh, A. J., Hall, R. J., Ferguson, K. J., …Cunningham, C. (2013). New horizons in the pathogenesis, assessment and management of delirium. Age and Aging, 42(6), 667-674. doi: 10.1093/ageing/aft148

      • The full-text version of this article can be accessed through the PubMed Central database in the Ashford University Library. This author of this article examines the cause, management, and treatment of delirium.

Ridley, N. J., Draper, B., & Withall, A. (2013). Alcohol-related dementia: An update of the evidence. Alzheimer’s Research & Therapy, 5(1), 3-11. doi: 10.1186/alzrt157

    • The full-text version of this article can be accessed through the PubMed Central database in the Ashford University Library. This author of this article examines the cause, management, and treatment of delirium.

khanacademymedicine. (2013, October 24). Alzheimer’s disease and Korsakoff’s syndrome [Video file]. Retrieved from http://youtu.be/qWfwRbSrQMU?list=PL8T3L0Uv8x9nWOGYQ0Q4-AUcAvLavw2oA

      • This video provides information on two important forms of dementia.

khanacademymedicine. (2014, June 25). Reward pathway in the brain [Video file]. Retrieved from http://youtu.be/YzCYuKX6zp8

    • This video provides information on the reward pathway and its’ role in addiction.

Answer Preview

Alzheimer’s disease, normally referred to as the Alzheimer’s, is one of the most common forms of dementia. Dementia is a condition of the brain, whereby an individual progressively loses their intellectual abilities and social skills. The brain cells of a person with Alzheimer’s tend to degenerate and die, resulting in a decline in the memory and the mental function of the individual. Over the years, Alzheimer’s disease has often been associated with age, with the most common incidences of dementia being reported in aging individuals of 65 years and older (Alzheimer’s Association, 2011).

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